Guler 1996.

Methods	Randomised Controlled Trial Double‐blind Placebo‐ controlled Parallel‐group ITT analysis
Participants	Country: Turkey Mean age: NR % Female: NR Mean disease duration: NR Duration: 10 wk Number randomised: 30 (HA 15, PL 15) Inclusion: Exclusion: Baseline values: WOMAC pain HA: 16.87 WOMAC stiffness HA: 6.47 WOMAC function HA: 59.00
Interventions	Orthovisc 15 mg/ml 2 ml once per week for 3 weeks Placebo: physiologic saline 2 ml Concurrent therapy: acetaminophen use recorded
Outcomes	WOMAC pain(5‐25), stiffness (2‐10) function (17‐85) ‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐‐ quantity of acetaminophen use time for 15 meter walk range of joint mobility patella ciricumference pt assessment of degree of arthrosis satisfaction with treatment
Notes	Jadad's: 3/5 R‐1,B‐1,W‐1
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear