| Methods |
Randomised
Controlled
Trial
Blind
Parallel‐group
ITT analysis |
| Participants |
Country:
Spain
Mean age: 65
% Female:84
Mean disease
duration:NR
Duration: 6 mth
Number randomised:49
(AD 30, HY 19)
Inclusion:
gonarthrosis by clinical and radiological criteria
(Kellgren and Lawrence Grade 2 to 3)
Exclusion:
NR |
| Interventions |
Adant (25 mg/2.5 ml) 5 weekly injections
Hyalgan (20 mg/2 ml) 5 weekly injections
Concurrent therapy:
Analgesics and/or
NSAIDs monitored |
| Outcomes |
pt efficacy assessment
(clinical improvement crieria rated as: excellent >75, good 50 to 75,
fair 25 to 50, no clinical
response <25)
consumption of analgesic and/or NSAIDS |
| Notes |
Jadad's:3/5
R‐1,B‐1,W‐1
Imbalance in sample size per group. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
