NCT00139295.

Trial name or title	Comparison of the efficacy and safety of Hylastan to methylprednisolone acetate in patients with symptomatic osteoarthritis of the knee
Methods
Participants	Males and females 40 years and above diagnosed with OA of the knee. Have tried but not been sufficiently helped by conservative treatment such as weight reduction and pain medications. Exclusion: prior or concomitant treatments that would impede measuremen tof safety and efficacy
Interventions	Hylastan and active control
Outcomes	Pain relief
Starting date	October 2004
Contact information	David Perkins, R.Ph., Study Director, Genzyme
Notes	Expected completion: March 2007, Data entry closure: December 2006