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LED setup of the in vitro cell irradiation system. a, Schematic of LED array on a printed circuit board (PCB) equipped with 3D printed support brackets to ensure adequate distance between the LED array and cell culture. A mobile power supply can also be placed in the incubator. b, Schematic diagram of PLA microneedles fixed on a cell culture insert. Microneedles puncture the membrane of the cell culture insert. c, Blue, green, and red 12-LED arrays mounted on PCBs.
