Jones 1996.

Methods	Randomised controlled trial 2‐arm cross‐over design Trial duration: 16 weeks
Participants	59 participants with knee osteoarthritis were randomised 59 participants were reported at baseline Number of females: 37 out of 59 (63%) Mean age: 70.6 years
Interventions	Experimental intervention 40 mg methyl prednisolone acetate (1 ml), single intra‐articular injection Control intervention 1 ml 0.9% saline, single intra‐articular injection Cross‐over after 8 weeks. Every participant received 1 injection (experimental and control) each
Outcomes	Extracted pain outcome: Pain on activities other than walking Maximum follow‐up: 8 weeks
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method used to generate random sequence of allocation was not reported, so the risk of selection bias was unclear
Allocation concealment (selection bias)	Unclear risk	Method used to conceal the random sequence of allocation was not reported, so the risk of selection bias was unclear
Blinding of participants?	Unclear risk	Quote: "Each injection was given by a second operator, thus blinding both patient and assessor." No further description of blinding
Blinding of health care provider(s)	Unclear risk	Quote: "Each injection was given by a second operator, thus blinding both patient and assessor." No further description of blinding
Intention‐to‐treat analysis performed? Pain	High risk	Quotes: "As some data was missing due to patient withdrawal, all analyses were performed on a last measures carried forward, intention to treat basis", but still not all participants randomised were analysed. Quote: "One patient failed to enter the study and received no injection, leaving 59 patients available for the analysis."
Intention‐to‐treat analysis performed? Function	Unclear risk	Not applicable, no function outcome reported