Petrella 2015.

Methods	Randomised controlled trial 2‐arm parallel‐group design Trial duration: 26 weeks
Participants	98 participants with knee osteoarthritis were randomised 98 participants were reported at baseline Number of females: 56 out of 98 (57%) Mean age: 59.7 years
Interventions	Experimental intervention 10 mg triamcinolone acetonide + hyaluronan solution (no dosage stated), 6 ml total, single intra‐articular injection Control intervention Hyaluronan solution (no dosage stated), single intra‐articular injection
Outcomes	Extracted pain outcome: WOMAC Pain Extracted function outcome: WOMAC Function Maximum follow‐up: 26 weeks
Notes	Funding: Carbylan Therapeutics
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "The randomization treatment was computer generated and was stratified by study center."
Allocation concealment (selection bias)	Unclear risk	Quote: "The randomization treatment was computer generated and was stratified by study center."
Blinding of participants?	Unclear risk	It was unclear if method used to blind participants was appropriate
Blinding of health care provider(s)	High risk	Quote: "An injecting physician delivered the randomized treatment and remained unblinded."
Intention‐to‐treat analysis performed? Pain	High risk	2 of 33 participants excluded in experimental group, 1 of 33 participants excluded in control group
Intention‐to‐treat analysis performed? Function	High risk	2 of 33 participants excluded in experimental group, 1 of 33 participants excluded in control group