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. 2015 Oct 22;2015(10):CD005328. doi: 10.1002/14651858.CD005328.pub3

Yavuz 2012.

Methods Randomised controlled trial
4‐arm parallel‐group design
Trial duration: 12 weeks
Participants 120 participants with knee osteoarthritis were randomised
120 participants were reported at baseline
Number of females: 76 out of 120 (63%)
Mean age: 60.0 years
Interventions Experimental intervention
Intervention (A): 40 mg triamsinolon acetonate (1 ml), single intra‐articular injection
Intervention (B): 3 mg betametazone disodium phosphate (1 ml), single intra‐articular injection
Intervention (C): 40 mg methylprednisolone acetate (1 ml), single intra‐articular injection
Control intervention
1 ml 0.9% sodium chloride, single intra‐articular injection
Outcomes Extracted pain outcome (A)‐(C): Pain overall
Extracted function outcome (A)‐(C): Lequesne index
Maximum follow‐up: 12 weeks
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Quote: "A total of 120 eligible patients with knee osteoarthritis were included (according to their admission date) and randomized into four groups."
Allocation concealment (selection bias) Unclear risk Method used to conceal the random sequence of allocation was not reported, so the risk of selection bias was unclear
Blinding of participants? Unclear risk It was unclear if participants were blinded
Blinding of health care provider(s) Unclear risk Physicians were not explicitly described as blinded, so the risk of performance bias was unclear
Intention‐to‐treat analysis performed? Pain Unclear risk It was unclear whether all participants randomised were also analysed
Intention‐to‐treat analysis performed? Function Unclear risk It was unclear whether all participants randomised were also analysed