Yavuz 2012.
Methods | Randomised controlled trial 4‐arm parallel‐group design Trial duration: 12 weeks |
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Participants | 120 participants with knee osteoarthritis were randomised 120 participants were reported at baseline Number of females: 76 out of 120 (63%) Mean age: 60.0 years |
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Interventions |
Experimental intervention Intervention (A): 40 mg triamsinolon acetonate (1 ml), single intra‐articular injection Intervention (B): 3 mg betametazone disodium phosphate (1 ml), single intra‐articular injection Intervention (C): 40 mg methylprednisolone acetate (1 ml), single intra‐articular injection Control intervention 1 ml 0.9% sodium chloride, single intra‐articular injection |
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Outcomes | Extracted pain outcome (A)‐(C): Pain overall Extracted function outcome (A)‐(C): Lequesne index Maximum follow‐up: 12 weeks |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Quote: "A total of 120 eligible patients with knee osteoarthritis were included (according to their admission date) and randomized into four groups." |
Allocation concealment (selection bias) | Unclear risk | Method used to conceal the random sequence of allocation was not reported, so the risk of selection bias was unclear |
Blinding of participants? | Unclear risk | It was unclear if participants were blinded |
Blinding of health care provider(s) | Unclear risk | Physicians were not explicitly described as blinded, so the risk of performance bias was unclear |
Intention‐to‐treat analysis performed? Pain | Unclear risk | It was unclear whether all participants randomised were also analysed |
Intention‐to‐treat analysis performed? Function | Unclear risk | It was unclear whether all participants randomised were also analysed |