Zhilyayev 2012.

Methods	Randomised controlled trial 4‐arm parallel‐group design Trial duration: 12 weeks
Participants	209 knees belonging to 112 participants were randomised Unclear number of participants with knee osteoarthritis reported at baseline Number of females: not stated Mean age: not stated
Interventions	Experimental intervention 20 mg triamcinolone acetonid plus 10 ml 0.5% procaine, single intra‐articular injection Control intervention 10 ml 0.5% procaine, single intra‐articular injection
Outcomes	Extracted pain outcome: WOMAC Pain Maximum follow‐up: 12 weeks
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "joints were randomized by envelopes to one of 4 treatments"
Allocation concealment (selection bias)	Unclear risk	Quote: "joints were randomized by envelopes to one of 4 treatments"
Blinding of participants?	Unclear risk	It was unclear if method used to blind participants was appropriate
Blinding of health care provider(s)	Unclear risk	Physicians were not explicitly described as blinded, so the risk of performance bias was unclear
Intention‐to‐treat analysis performed? Pain	Unclear risk	It was unclear whether all participants randomised were also analysed
Intention‐to‐treat analysis performed? Function	Unclear risk	Not applicable, no function outcome reported

IA: intra‐articular
 WOMAC: Western Ontario and McMaster Universities Arthritis Index