Fig 4. Initiation of wound healing and visual assessment of the angiogenic response during the treatment of the wounds with AUP1602-C or vehicle.

A) wound healing initiation, B) scoring of visual assessment of angiogenic response with green and red dots indicating the individual mean score from two observers and C) example images for defining the clinical score regarding the visual assessment of angiogenesis. All data are presented as mean ± SEM. Statistical analysis was performed with Fisher’s exact test. ns = non-significant, *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.