Table 5. Clinical features of children with mutated P falciparum in this study.
| Study site | Sample ID | Gender | Age (Month) | Enrollment asexual parasitaemia (uL-1) | Mutation Position | Parasite clearance time (day) | Antimalarial Treatment | Treatment outcome |
|---|---|---|---|---|---|---|---|---|
| Enugu | 33 | M | 48 | 30571 | A578S | 1 | AL | ACPR |
| 89 | F | 60 | 12817 | Q613H | 2 | AL | ACPR | |
| 106 | F | 36 | 16290 | Q613H | 2 | AL | ACPR | |
| 134 | M | 72 | 57850 | A621A | 2 | AL | ACPR | |
| 154 | M | 60 | 3424 | V487E | 2 | AL | ACPR | |
| 179 | M | 36 | 61320 | A557S | 2 | DHP | ACPR | |
| 197 | M | 48 | 2055 | C469C | 2 | DHP | LPF (D42) | |
| 228+ | F | 24 | 91680 | C469C | 2 | AL | LPF (D21) | |
| 236 | M | 36 | 9794 | C469C | 2 | AL | LPF (D28) | |
| 239 | M | 72 | 6714 | V692G | 1 | AL | LPF (D28) | |
| Q661H | ||||||||
| 254 | M | 96 | 29229 | C469C | 2 | AL | LPF (D28) | |
| Kano | ||||||||
| 14 | M | 12 | 15923 | N694K | 2 | AA | ACPR | |
| 26 | F | 24 | 37880 | F451L | 1 | AL | ACPR | |
| 51 | F | 84 | 26523 | K438N | 2 | AA | ACPR | |
| 59 | M | 36 | 16888 | G449S | 2 | AL | ACPR | |
| 77 | M | 48 | 2250 | G449S | 1 | AA | ACPR | |
| Plateau | 31 | F | 84 | 26069 | Q613H | 1 | AA | ACPR |
| 58 | M | 60 | 16304 | Q613H | 1 | AL | ACPR | |
| 62 | F | 72 | 61080 | Q613H | 2 | AL | ACPR | |
| 77 | F | 60 | 5428 | N664I | 1 | AL | LPF (D28) | |
| 155 | M | 60 | 54739 | V692G | 2 | AA | LPF (D28) | |
| Mean (SD) | 53.71 (22) | 17, 530* | 1.67 (0.48) | 29 (6.3)# |
*Geometric mean;
#Mean LPF;
+Only sample with recrudescence recurrent parasitaemia.