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. 2022 Feb 24;15:1331–1345. doi: 10.2147/JIR.S354095

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© 2022 Frühbeck et al.

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The expression of IL1RN in visceral adipose tissue (VAT) is increased in patients with obesity and impaired glucose (IGF) intolerance or type 2 diabetes (T2D). (A) Levels of IL1RN mRNA in VAT of subjects with normal weight (NW), obesity and normoglycemia (OB-NG), and obesity and IGT or T2D (OB-IGT&T2D). Bars represent the mean ± SD of the ratio between IL1RN to 18S rRNA. The expression of IL1RN in NW subjects was assumed to be 1. Differences between groups were analyzed ANOVA followed by LSD tests. **P<0.01. Scatter diagrams showing the correlations between IL1RN mRNA and the mRNA expression levels of (B) SPP1, (C) TNF, (D) CCL2, (E) CD68, (F) MMP9, and (G) VEGFA in VAT. Pearson’s correlation coefficient (r) and P values are indicated.