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. Author manuscript; available in PMC: 2022 Feb 28.
Published in final edited form as: FASEB J. 2019 Dec 10;34(1):1846–1858. doi: 10.1096/fj.201902214R

Figure 3. Hepatocyte-specific p53 ablation impairs glucose homeostasis which is normalized by VSG and food restriction.

Figure 3.

A) Fasting blood glucose concentrations at baseline, one month and three months after surgery. B) Fasting serum insulin concentrations at the time of OGTT. C) Blood glucose concentrations D) and percent change in insulin from baseline to 15 minutes after the glucose gavage during an OGTT at 2 months after surgery. *p<0.05, **p<0.01, ***p<0.001 VSG compared with S-AL; +p<0.05 VSG compared with S-WM; #p<0.05, ###p<0.001 S-AL-KO compared with S-AL-WT by two-factor or three-factor ANOVA.