Figure 3.

Cystatin SN concentration in various biological matrices in healthy individuals. Concentration of cystatin SN in each biological fluid (mean ± standard deviation [s.d.]; n = 28 [n = 13 healthy controls ≤ 40 years old + n = 15 healthy controls 41–60 years old]), since Table 1 shows a significant increase in the cystatin SN concentration in the serum of 61–80 year old healthy controls, and thus, this age group was not included; cerebral spinal fluid (CSF) was obtained from an additional and separate group of cancer-free neurosurgical patients (n = 8) for the determination of the cystatin SN concentration as described in the Materials and methods section.

^a Significant difference (p < 0.001) from the mean value indicated with the same letter.

^b Significant difference (p < 0.05) from mean values indicated with the same letter.

^c Significant difference (p < 0.001) from the mean value indicated with the same letter.

^d Significant difference (p < 0.01) from the mean value indicated with the same letter.

^e Significant difference (p < 0.001) from the mean value indicated with the same letter.