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. 2022 Feb 14;13:784729. doi: 10.3389/fphar.2022.784729

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Copyright © 2022 Luo, Huang, Li, He, Meng, Huang, Shen and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network pharmacology predicted the active ingredients-target interactions for XBS against pediatric pneumonia. (A) The network of Herbs-active ingredients connection. The red nodes represent ingredients in XBS while the blue ones represent active ingredients. (B) The venn diagram for ingredients and pneumonia targets. The 128 overlap targets common between the predicted XBS targets and the pneumonia-related targets. (C) Network of targets predicted via the XBS-active ingredients. Blue nodes represent the active ingredients in XBS, whereas the yellow nodes represent the predicted targets. The edges represent the interaction between compounds and targets. (D) PPI network of the XBS ingredients targets against pediatric pneumonia.