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. 2022 Feb 14;12:767693. doi: 10.3389/fcimb.2022.767693

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Copyright © 2022 Lin, Zhang, Lin, Lin and Zuo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential abundance of operational taxonomic unit (OTU) associated with cervical intraepithelial neoplasia (CIN) in the vagina and cervix. (A) Volcano plot showing perturbated OTUs in the vagina. (B) Volcano plot showing perturbated OTUs in the cervix. (C) Correlation of Z-transformed significance of top significant OTUs between the vagina and cervix. (D) Venn diagram showing shared significant (p < 0.01) OTUs associated with CIN between the vagina and cervix.