Table 6.
Adverse events in included RCTs.
| Interventions | Study (reference) | Sample size | Adverse events |
|---|---|---|---|
| MA | Chen (2021) [38] | 40 | 1 case |
| Zhang (2019) [45] | 33 | 1 case of fatigue; 1 case of dizziness; 1 case of drowsiness | |
| Liu (2019) [51] | 44 | 1 case | |
| Huang (2018a) [55] | 32 | 1 case of hyperpigmentation | |
| Yan (2018) [56] | 36 | 1 case of dizziness; 1 case of gastrointestinal reaction; 1 case of fatigue; 1 case of rash; 1 case of pruritus | |
| Li (2018b) [59] | 44 | 1 case of nausea and vomiting | |
| Xiao (2016) [67] | 50 | 1 case of dizziness | |
| Li (2016) [69] | 25 | 1 case | |
| Zhou (2016) [72] | 32 | 1 case | |
| Liu (2016) [73] | 30 | 1 case of dizziness; 1 case of fatigue | |
| Xie (2016) [74] | 40 | 2 cases | |
| Liu (2015) [75] | 42 | 3 cases of drowsiness | |
| Wang (2015) [76] | 35 | 2 cases | |
| Xia (2015) [77] | 30 | 1 case | |
| CM | Chen (2021) [38] | 40 | 6 cases |
| Chi (2021) [39] | 39 | 2 cases of drowsiness; 3 cases of dizziness; 3 cases of nausea and vomiting | |
| Zhang (2019) [45] | 29 | 2 cases of fatigue; 1 case of dizziness; 2 cases of drowsiness; 2 cases of gastrointestinal reaction | |
| Xu (2019) [48] | 33 | 1 case of dizziness; 1 case of drowsiness; 2 cases of nausea | |
| Liu (2019) [51] | 44 | 6 cases | |
| Si (2018) [53] | 33 | 2 cases of peripheral facial paralysis; 4 cases of facial numbness; 5 cases of tinnitus; 6 cases of herpesvirus infection | |
| Liang (2018) [54] | 43 | 1 case of dizziness; 2 cases of nausea and vomiting; 3 cases of drowsiness; 1 case of fever; 1 case of pruritus | |
| Huang (2018a) [55] | 31 | 1 case of dermatitis; 5 cases of drowsiness | |
| Yan (2018) [56] | 36 | 3 cases of dizziness; 4 cases of gastrointestinal reaction; 1 case of fatigue; 2 cases of rash; 3 cases of pruritus | |
| Li (2018b) [59] | 44 | 1 case of rash; 2 cases of pruritus; 1 case of dizziness; 3 cases of fatigue | |
| Shen (2016) [66] | 40 | 1 case of dermatitis; 6 cases of dizziness | |
| Xiao (2016) [67] | 50 | 6 cases of gastrointestinal reaction; 4 cases of abnormal liver function; 2 cases of rash | |
| Li (2016) [69] | 25 | 5 cases | |
| Zhou (2016) [72] | 32 | 6 cases | |
| Liu (2016) [73] | 30 | 1 case of dizziness; 1 case of gastrointestinal reaction; 2 cases of fatigue; 1 case of nausea | |
| Xie (2016) [74] | 40 | 8 cases | |
| Liu (2015) [75] | 42 | 3 cases of dizziness; 5 cases of drowsiness; 3 cases of nausea | |
| Wang (2015) [76] | 35 | 8 cases | |
| Xia (2015) [77] | 30 | 5 cases | |
| Zhang (2013) [83] | 28 | 5 cases of dizziness; 6 cases of gastrointestinal reaction | |
| Luo (2013) [85] | 20 | 3 cases of dizziness; 5 cases of drowsiness; 1 case of xerostomia; 2 cases of nausea and vomiting; 2 cases of anorexia; 2 cases of skin disorders | |
| Zhao (2009) [89] | 20 | 1 case of dizziness; 3 cases of drowsiness; 3 cases of xerostomia; 4 cases of nausea and vomiting; 3 cases of anorexia; 6 cases of constipation; 1 case of abnormal liver function; 3 cases of abnormal blood; 1 case of abnormal renal function; 2 cases of restless; 8 cases of skin disorders | |
| SA | Liu (2014) [80] | 28 | 1 case of dizziness |
| Chi (2021) [39] | 39 | 1 case of dizziness; 1 case of nausea and vomiting | |
| Shen (2016) [66] | 40 | 2 cases of hyperpigmentation | |
| MA + CM | Zhao (2009) [89] | 20 | 4 cases of dizziness; 7 cases of drowsiness; 6 cases of xerostomia; 1 case of nausea and vomiting; 12 cases of anorexia; 6 cases of constipation; 3 cases of abnormal liver function; 2 cases of abnormal blood; 2 cases of abnormal renal function; 3 cases of restless; 2 cases of skin disorders |
| EA + CM | Si (2018) [53] | 33 | 1 case of peripheral facial paralysis; 1 case of facial numbness; 3 cases of tinnitus; 2 cases of herpesvirus infection |
| AM + CM | Xu (2019) [48] | 33 | 2 cases of dizziness |
MA: manual acupuncture; EA: electronic acupuncture; SA: sham acupuncture; AM: acupuncture-moxibustion; CM: conventional medicine.