Table 2.
Univariate and Multivariate Analysis of Variables Related to Risk of Negative Response After the Third Dose in Kidney Transplant Recipients
| Univariate Analysis |
Multivariate Analysis |
|||||
|---|---|---|---|---|---|---|
| Variable | Exp (B) | 95% CI | P value | Exp (B) | 95% CI | P value |
| Age (y) | 1.07 | 1.02-1.12 | .002 | 1.054 | 1.01-1.14 | .03 |
| Antibody level before booster (AU/mL) | 0.93 | 0.90-0.97 | <.001 | 0.93 | 0.89-0.98 | .002 |
| Sex | 0.95 | 0.4-1.7 | .92 | - | - | - |
| Donor (deceased vs living) | 1.3 | 0.79-3.3 | .52 | - | - | - |
| eGFR, mL/min | 0.97 | 0.95-0.99 | .03 | 0.97 | 0.92-1.01 | .15 |
| BMI | 0.97 | 0.83-1.15 | .62 | - | - | - |
| Time on dialysis (mo) | 1.1 | 0.9-1.27 | .12 | - | - | - |
| MMF | 1.04 | 1.01-1.3 | .05 | 1.01 | 0.99-1.3 | .28 |
| Lymphocyte count | 0.81 | 0.73-0.75 | .03 | 0.97 | 0.91-0.99 | .04 |
| Time since transplantation, months | 0.97 | 0.92-1.06 | .07 | 0.97 | 0.96-1.11 | .17 |
BMI, body mass index; CI, confidence interval; eGFR, estimated glomerular filtration rate; MMF, mycophenolate mofetil or mycophenolate sodium.