Table 3.

Dose recommendations for Contact X-Ray Brachytherapy (see appendix 1 to describe the Grade of recommendation).

Stage	Dose and number of fractions	Notes
Initial Treatment
Post excision (low-risk T1, see Table 2)	Preferred 40–60 Gy in 2F, Grade B Acceptable 50 Gy in 3F (20 Gy/15 Gy/15 Gy), Grade C
Post excision (T2 or high-risk T1, see Table 2)	Preferred 40–60 Gy in 2F (completely excised) 90 Gy in 3F (disease residual), Grade B	With EBRT 45–50 Gy/25F + capecitabine if fit or 25 Gy/5F if less fit
T1N0	110 Gy in 4F (30 Gy/30 Gy/30 Gy/20 Gy), Grade C	If inadequate tumour response at 3rd F fit patients should proceed to surgery and unfit patients should have 3rdF and then have EBRT 45–50 Gy/25F + capecitabine if fit or 25 Gy/5F if less fit
T2/3N0/1 (surgically fit) T4 or any N2 (surgically unfit or palliative)	Preferred 90 Gy in 3F (30 Gy/30 Gy/30 Gy), Grade C Acceptable 85 Gy in 3F (30 Gy/30 Gy/25 Gy), Grade B 110 Gy in 4F (30 Gy/30 Gy/30 Gy/20 Gy), Grade D	With EBRT 45–50 Gy/25F + capecitabine if fit or 25 Gy/5F if less fit
Retreatment
Any	90 Gy in 3F (30 Gy/30 Gy/30 Gy) 110 Gy in 4F (30 Gy/30 Gy/30 Gy/20 Gy), Grade D	Consideration must be given to previous radiotherapy doses

Abbreviations.

EBRT external beam radiotherapy.

F fraction.

Gy Gray.