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. 2021 Oct 21;36(3):781–789. doi: 10.1038/s41375-021-01444-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Oncoplot showing TP53 status (upper panel) and associated complex chromosomes (lower panel). Histogram displaying the frequency of complex abnormalities of each chromosome arm in biallelic, monoallelic and TP53 normal groups. As a diagnosis of BLL-11q is determined by the presence of a complex 11q rearrangement, these five cases were excluded from this analysis. TP53 Biallelic with 1q complexity vs TP53 Normal with 1q complexity, p = 0.026; TP53 Biallelic with 11q complexity vs TP53 Normal with 11q complexity, p = 0.006. TP53 Biallelic with 13q complexity vs TP53 Normal with 13q complexity, p = 0.001; TP53 Biallelic with 13q complexity vs TP53 Monoallelic with 13q complexity, p = 0.002. Fisher’s Exact test * = p < 0.05, ** = p < 0.01; ^# Li-Fraumeni syndrome case.