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| Study name (year of publication) | START B (2008) | Whelan et al.10 (2010) | DBCG HYPO (2020) | Current study |
|---|---|---|---|---|
| No. of patients | 2,215 | 1,234 | 1,882 | 178 |
| whole breast dose (cGy) | 4,000 | 4,256 | 4,000 | 4,240–4,256 |
| whole breast fractions | 15 | 16 | 15 | 16 |
| FU period (yr) | 5 | 10 | 9 | 2 |
| local failure (IBTR, %) | 2.2 | 6.7 | 3.3 | 0 |
| P value | 0.21 | 0.75 | 0.41 | 0.37 |
FU = follow up, IBTR = ipsilateral breast tumor recurrence.
