Table 1.
Baseline characteristics of chest pain patients included in this study.
| Characteristics |
AAD (n = 96) |
Controls(n = 249) | P-value | |
|---|---|---|---|---|
| Age, mean (range) | 59.1 (35–85) | 60.3 (40–92) | 0.45 | |
| Male sex, n (%) | 53 (55.2) | 128 (51.4) | 0.53 | |
| Medical history and risk factors, n (%) | ||||
| Hypertension | 72 (75.0) | 129 (51.8) | <0.05 | |
| Diabetes | 44 (45.8) | 109 (43.8) | 0.62 | |
| Stroke | 28 (29.2) | 80 (32.1) | 0.60 | |
| Hyperlipidemia | 48 (50.0) | 135 (54.2) | 0.48 | |
| Smoking | 55 (57.3) | 125 (50.2) | 0.24 | |
| Marfan syndrome | 12 (12.5) | 1 (0.4) | <0.01 | |
| Atrial fibrillation | 28 (29.2) | 63 (25.3) | 0.47 | |
| Valvulopathy | 20 (20.8) | 42 (16.9) | 0.39 | |
| Diagnosis, n (%) | ||||
| TAAD | 42 (43.8) | / | / | |
| TBAD | 54 (56.3) | / | / | |
| IH | / | 10 (4.0) | / | |
| AMI | / | 63 (25.3) | / | |
| PE | / | 42 (16.9) | / | |
| Angina | / | 66 (26.5) | / | |
| Others | / | 68 (27.3) | / | |
| Biochemical and hematological data, mean ±SD | ||||
| Glucose, mg/dL | 130.3 ± 52.4 | 125.4 ± 44.2 | 0.42 | |
| Creatinine, μmol/L | 148.7 ± 33.6 | 142.9 ± 40.7 | 0.36 | |
| Uric acid, mg/dL | 6.1 ± 2.4 | 5.9 ± 2.9 | 0.37 | |
| Cholesterol, mg/dL | 178.3 ± 39.2 | 183.2 ± 29.9 | 0.72 | |
| Triglycerides, mg/dL | 182.1 ± 88.4 | 189.1 ± 79.2 | 0.60 | |
| AST, U/L | 28.2 ± 13.4 | 30.2 ± 20.2 | 0.13 | |
| ALT, U/L | 38.3 ± 16.7 | 39.6 ± 26.3 | 0.22 | |
| Bilirubin, mg/dL | 1.9 ± 1.6 | 1.8 ± 0.8 | 0.82 | |
| Hematocrit, % | 41.3 ± 6.3 | 39.4 ± 5.6 | 0.63 | |
| Platelets, 103/μL | 248.3 ± 56.4 | 256.6 ± 47.2 | 0.20 | |
| Leukocytes, 103/μL | 6.4 ± 3.4 | 6.8 ± 3.9 | 0.74 | |
| Lymphocytes, % | 26.3 ± 9.2 | 27.5 ± 8.4 | 0.20 | |
| Neutrophils, % | 74.4 ± 18.3 | 73.9 ± 19.8 | 0.48 | |
| Monocytes, % | 8.8 ± 4.2 | 9.0 ± 7.3 | 0.33 | |
| D-dimer, ng/ml | 2080.5 ± 1131.9 | 1867.3 ± 2007.3 | <0.05 | |
AAD, acute aortic dissection; TAAD, type A aortic dissection; TBAD, type B aortic dissection; IH, intramural hematoma; AMI, acute myocardial infarction; PE, pulmonary embolism; SD, standard deviation; AST, aspartate transaminase; ALT, alanine aminotransferase.