Figure 1.

T-cell proliferation to IL-2 + CD3/28 stimulation. (A) Individual examples of CD4⁺ and CD8⁺ T-cell proliferation at Day 4, determined by CellTrace Violet (CTV) dilution. (B) Proportions of dividing cells at Day 4 for each cohort, expressed as a percentage of total CD3⁺, CD4⁺ and CD8⁺ T-cells. Results presented as means and standard errors of the mean (SEM). (C) T-cell proliferation over time: number of CD4⁺ and CD8⁺ divisions at each time-point, expressed as a percentage of total CD4⁺ and CD8⁺ T-cells. Results presented as means and SEM for each cohort. MDN, Mean Division Number.