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. 2022 Feb 15;10:837032. doi: 10.3389/fchem.2022.837032

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Copyright © 2022 Li, Guo, Zhang, Li and Hao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Magnetic resonance contrast enhancement analysis of Gd₂O₃@mesoporous silica nanoparticles (MSN) and Gd-gadolinium diethylene triamine pentaacetate (DTPA). Analysis of the relaxation rate r ₁ versus gadolinium ion concentration for Gd₂O₃@MSN and Gd-DTPA in a 0.5T magnetic field (A); T₁-weighted phantom images produced from Gd₂O₃@MSN and Gd-DTPA under a 3T field (B); (C) signal-to-noise ratios of Gd₂O₃@MSN and Gd-DTPA at varying Gd concentrations.