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. 2022 Feb 28;7:18. doi: 10.1038/s41536-022-00213-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Scheme for the construction of the matrix-sutured model. A porcine native kidney (left) is subjected to PN (middle), then the organ-derived matrix is sutured onto the resected surface of the native kidney (right). b Scheme for the construction of the control model. A porcine native kidney is only subjected to PN. c Photographs of a harvested kidney containing an organ-derived matrix sutured to residual kidney 28 days postimplantation. The white arrows show the implanted organ-derived matrix. d Photographs of a harvested PN kidney 28 days post-surgery. c, d The images on the right show the sagittal section of the harvested kidneys. e Comparison of the resection rate between the PN kidney (control) and the matrix-sutured kidney. Bars represent the mean ± SD, (n = 4). f Comparison of the major axes between the harvested PN kidney (control) and matrix-sutured kidney. Bars represent the mean ± SD, (n = 4). g Experimental outline of the porcine PN model (control) and the matrix-sutured model. The following four types of harvested kidneys were analyzed: PN kidney 28 days postsurgery (control, sample 1), healthy kidney (sample 2), organ-derived matrix 28 days post-implantation (sample 3), and corresponding residual kidney 28 days post-implantation (sample 4).