Table 1.

CompBio in silico analysis of bulk RNA sequencing data showing significantly altered pathways in livers from NAMPT OE and WT controls.

	SIRT-dependent	SIRT1-independent
Increased NAMPT OE vs. WT	PI3K/AKT signaling NFкB Signaling T cell Regulation	Neutrophil Chemotaxis Complement Pathway
Decreased NAMPT OE vs. WT	NASH Lipid metabolism	De novo lipogenesis Hepatic Steatosis Retinoic acid Adipogenesis