Table 1.
Demographic and baseline characteristics of patients.
| Characteristics | mNGS group (n = 173) | Control group (n = 173) | P |
|---|---|---|---|
| Age, mean (range), years | 60 (15–87) | 64 (18–90) | 0.045 |
| Sex, female, n (%) | 47 (27.2) | 67 (38.7) | 0.030 |
| Hospital, mean (range), days | 16 (1–66) | 11 (0–70) | 0.001 |
| Comorbidity, n (%) | |||
| Cardiovascular disease | 34 (20.0) | 35 (20.2) | 1.000 |
| Hypertension | 43 (24.9) | 51 (29.5) | 0.398 |
| Chronic obstructive pulmonary disease | 19 (11.0) | 17 (9.8) | 0.860 |
| Neoplastic disease | 17 (9.8) | 25 (14.5) | 0.249 |
| Diabetes | 27 (15.6) | 30 (17.3) | 0.772 |
| Kidney disease | 8 (4.6) | 12 (6.9) | 0.490 |
| Bronchiectasis | 16 (9.2) | 16 (9.2) | 1.000 |
| Cerebrovascular disease | 22 (12.7) | 26 (15.0) | 0.641 |
| ARDS, n (%) | 49 (28.3) | 30 (17.3) | 0.021 |
| On empiric antibiotics at time of sample collection, n (%) | 173 (100) | 171 (98.8) | 0.499 |
| Apache II score, mean ± standard deviation | 14.0 ± 5.4 | 12.2 ± 6.4 | 0.051 |
| 30-day mortality, n (%) | 14 (8.1) | 12 (6.9) | 0.839 |
mNGS, metagenomic next generation sequencing; ARDS, acute respiratory distress syndrome.