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. 2022 Feb 28;8:90. doi: 10.1038/s41420-022-00894-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Schematic diagram of experimental design of DMF treatment for CS-AKI mice. b, c qPCR analyses KIM-1 and NGAL mRNA level in the renal tissues of four groups (NC, CS, CS + DMF, DMF). d–g Concentration of biochemical indicators CK, myoglobin, SCr and BUN in serum. h Evaluation of the therapeutic effect of DMF on the kidney tissue of CS-AKI mice by HE staining (original magnification: 200×, scale bar: 100 μm). i IHC staining analyses the expression of NGAL in kidney tissues (original magnification: 200×, scale bar: 100 μm). For statistical analysis, one-way ANOVA followed by Tukey’s method for multiple comparisons used in (b–g). Data are expressed as mean ± SD, n = 3 per group. **P < 0.01, ***P < 0.001.