Table 7.
Inter- and intra-day accuracy and precision for the determination of total alkaloid in rat plasma (n = 5).
| Name | Spiked concentration (ng/mL) | Inter-day | Intra-day | ||||
|---|---|---|---|---|---|---|---|
| Concentration (mean ± SD) | Precision (%) | Accuracy (%) | Concentration (mean ± SD) | Precision (%) | Accuracy (%) | ||
| Matrine | 1.56 | 1.58 ± 0.02 | 1.27 | 1.28 | 1.57 ± 0.03 | 1.91 | 0.64 |
| 25.00 | 26.92 ± 1.39 | 5.16 | 7.68 | 26.25 ± 0.89 | 3.39 | 5.00 | |
| 100.00 | 107.63 ± 4.87 | 4.52 | 7.63 | 104.70 ± 1.56 | 1.49 | 4.70 | |
| Oxymatrine | 1.56 | 1.57 ± 0.04 | 2.55 | 0.64 | 1.66 ± 0.05 | 3.01 | 6.41 |
| 25.00 | 26.58 ± 0.81 | 3.05 | 6.32 | 26.90 ± 0.22 | 0.82 | 7.60 | |
| 100.00 | 107.26 ± 3.54 | 3.30 | 7.26 | 106.88 ± 0.85 | 0.80 | 6.88 | |
| Sophocarpine | 1.56 | 1.55 ± 0.04 | 2.58 | 6.41 | 1.54 ± 0.02 | 1.30 | 1.28 |
| 25.00 | 24.00 ± 1.46 | 6.08 | 4.00 | 26.68 ± 2.04 | 7.65 | 6.72 | |
| 100.00 | 107.99 ± 2.67 | 2.47 | 7.99 | 105.31 ± 0.91 | 0.86 | 5.31 | |
| Sophoridine | 1.56 | 1.53 ± 0.01 | 0.65 | 1.92 | 1.57 ± 0.03 | 1.91 | 0.64 |
| 25.00 | 26.32 ± 0.99 | 3.76 | 5.28 | 26.37 ± 1.83 | 6.94 | 5.48 | |
| 100.00 | 106.23 ± 2.67 | 2.51 | 6.23 | 107.44 ± 0.55 | 0.51 | 7.44 | |