Figure 8.
Comparison of the intrinsic efficacy of each agonist in the indicated assays as determined by (A) calculated pK* (potency values were not included for morphine at Gai and cAMP and buprenorphine at βarr2), (B) Emax with SEM from SS-Table 2, and (C) τ as shown in Figure 2 as derived from log(τ) (SS-Table 1). Missing values in panel A for morphine are indicated by interrupted lines. Changes in rank order efficacy are easily visualized by the intersection of lines.