Table 3.

Adjusted logistic random intercept models of methamphetamine use with outcomes social adversity, sexual risk behaviors and STIs, HIV-related factors, and chronic health conditions among mSTUDY participants (Aug 2, 2014 to June 5, 2019)

	Methamphetamine use (past 6 mos.) ^a
	Monthly or less			Weekly or more
Dependent variables	AOR ^b	95% CI	p	AOR ^b	95% CI	p
Social adversity
Unemployment	3.7	2.4, 5.8	< .001	7.3	4.3, 12.3	< .001
Housing instability (past 6 mos.)	3.4	2.2, 5.3	< .001	6.7	4.1, 11.0	< .001
Intimate partner violence (past 12 mos.)	2.2	1.3, 3.6	.002	4.3	2.5, 7.3	.003
Sexual risk behaviors and STIs
New anal intercourse partner (past 6 mos.)	1.8	1.2, 2.6	.003	3.2	2.1, 4.8	< .001
Concurrent sexual partners (past 6 mos.)	2.0	1.3, 3.0	.001	4.8	3.0, 7.7	< .001
Exchange sex (past 3 mos.)	4.8	2.8, 8.1	< .001	15.5	8.9, 26.9	< .001
Positive STI test (chlamydia, gonorrhea, and/or syphilis)	1.4	0.9, 2.0	.105	2.3	1.6, 3.4	< .001
HIV-related factors
Detectable viral load (> 20 c/mL) ^c	1.4	0.8, 2.4	.146	3.2	1.8, 5.5	< .001
PrEP use (past 6 mos.) ^d	1.3	0.7, 2.5	.406	0.7	0.3, 1.6	.402
Chronic health conditions
Cardiovascular condition	1.4	0.9, 2.2	.130	1.3	0.8, 2.2	.246
Hepatic abnormality	0.8	0.4, 1.8	.596	1.8	0.9, 3.6	.108
Renal condition	1.2	0.6, 2.4	.642	2.1	1.0, 4.4	.047
Neurological condition	1.2	0.7, 1.9	.570	1.9	1.2, 3.1	.008
Psychological condition	1.3	0.9, 1.9	.111	1.9	1.3, 2.8	.001

Abbreviation: AOR = Adjusted odds ratio; CI = Confidence interval

Reference group is “None” or no methamphetamine use

Estimates adjust for age at visit, race, HIV status, current cigarette smoking, binge drinking (past 6 months), and within-person correlations between repeated measurements

Measured in HIV-positive participants only

Measured in HIV-negative participants only