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. 2022 Feb 5;22(1):105–112. doi: 10.1007/s40268-022-00382-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — NLR family Pyrin domain-containing receptor 3 (NLRP3) inflammasome was activated in the visceral adipose tissue and placenta of mice with gestational diabetes mellitus (GDM). The visceral adipose tissue and placenta were isolated from wild-type mice and GDM mice on gestational day (GD) 1, GD 8, and GD 15 for examining the activation of the NLRP3 inflammasome. The expressions of NLPR3 in the visceral adipose tissue (A–C) and placenta (D–F) were detected via western blot. P-values for the analysis of variance in panels B, C, E, and F were 0.0027, 0.0081, 0.0045, and 0.0019, respectively