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. Author manuscript; available in PMC: 2023 Apr 27.
Published in final edited form as: Chem Rev. 2021 Sep 1;122(8):7909–7951. doi: 10.1021/acs.chemrev.1c00696

Figure 11.

Figure 11.

UniDec-based “double FT” analysis of native mass spectrum of Nanodiscs containing mixtures of POPC and either PO-phosphatidylserine (POPS) or PO-phosphatidylglycerol (POPG) lipids. Example pure POPC Nanodisc native mass spectrum (A), corresponding Fourier spectrum (B) and “double FT” spectrum (C), revealing apparent average lipid mass (yellow dot). Measured apparent average lipid masses for different bulk lipid compositions (D, E) and reconstructed Nanodisc lipid composition versus bulk lipid composition (F). Reprinted with permission from ref. 302. © 2016 American Chemical Society.