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Representative native mass spectra of globular proteins (A: chicken-egg lysozyme, B: bovine β-lactoglobulin, C: human transferrin) and intrinsically disordered proteins (IDPs; D: Sic1-KID from Saccharomyces cerevisiae residues 215-284, E: human stathmin-4, F: murine ataxin-3 residues 1-291), illustrating relatively low charge states for globular proteins and multimodal distributions for IDPs. Reprinted with permission from ref. 548. © 2017 American Society for Mass Spectrometry.
