Table 3.
Arterial blood gas analysis, details of respiratory function at admission and follow-up, length of stay at ICU and hospital for all patients and subgroups
| All patients, n = 90 | Vaccinated, n = 36 | Unvaccinated, n = 54 | P | |
|---|---|---|---|---|
| Arterial blood gas | ||||
| pH, mean ± s.d. | 7.37 ± 0.12 | 7.38 ± 0.10 | 7.36 ± 0.13 | 0.483 |
| PaCO2, mmHg, median (IQR) | 36.60 (30.32–42.62) | 35.8 (29.87–44.35) | 36.70 (30.55–42.15) | 0.837 |
| PaO2, mmHg, median (IQR) | 76.70 (57.07–114.05) | 70.70 (48.02–120.75) | 77.10 (60.40–110.275) | 0.313 |
| SpO2, %, mean ± s.d. | 88.96 ± 13.82 | 83.71 ± 19.50 | 92.36 ± 6.59 | 0.003 |
| PaO2/FIO2 ratio | 80 (50–120) | 80 (40–105) | 90 (60–150) | 0.071 |
| Respiratory condition at admission, % | 0.135 | |||
| Room air | 1.1 | 2.8 | – | |
| Nasal oxygen | 11.1 | 2.8 | 16.7 | |
| NIMV | 46.7 | 50 | 44.4 | |
| IMV | 41.1 | 44.4 | 38.9 | |
| IMV, overall, % | 80 | 72.2 | 85.2 | 0.132 |
| Time to intubation, days, median (IQR) | 2.5 (1–6.75) | 4.5 (1–10.5) | 2.5 (1–6) | 0.711 |
| Duration of intubation, days, median (IQR) | 8 (3–14) | 7.5 (3–15.5) | 8 (2.5–14) | 0.986 |
| Hospital stay, days, median (IQR) | 15 (8–24) | 11 (6.25–22.5) | 15 (10–25) | 0.092 |
| ICU stay days, median (IQR) | 9 (5–14) | 7.5 (3–12.75) | 10 (6–14) | 0.204 |
| ICU mortality rate, % | 70 | 69.4 | 83.3 | 0.11 |
| Hospital mortality rate, % | 66 | 75 | 72.2 | 0.70 |
IMV, invasive mechanical ventilation; IQR, interquartile range; NIMV, non-invasive mechanical ventilation; s.d., standard deviation.