Skip to main content
. 2022 Feb 15;13:821533. doi: 10.3389/fimmu.2022.821533

Table 3.

Human KIR and their cognate ligands.

Inhibitory KIR Activating KIR
KIR2DL1 HLA-C2 epitope KIR2DS1 HLA-C2 epitope
KIR2DL2/3 HLA-C1 epitope KIR2DS2 Unknown
KIR2DL4 HLA-G KIR2DS3 Unknown
KIR2DL5A/B Unknown KIR2DS4 Subsets of HLA-C and HLA-A*11
KIR3DL1 HLA-A and HLA-B alleles encoding Bw4 epitope KIR2DS5 HLA-C (variable)
KIR3DL2 HLA-A*03 and HLA-A*11 KIR3DS1 HLA-F
KIR3DL3 Unknown KIR2DL4 HLA-G

Adapted from Boudreau and Hsu, Natural killer cell in human health and disease (65).