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. 2022 Feb 15;16:823060. doi: 10.3389/fnins.2022.823060

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Copyright © 2022 Albizzati, Florio, Miramondi, Sormonta, Landsberger and Frasca.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptional expression of astrocytic genes in the dorsal hippocampus of moderate and severe symptomatic Mecp2 KO animals. (A,B) The graphs depict the mRNA expression of selected astrocytic genes in motor cortex of moderate [at P40 (A)] and severe symptomatic [at P70 (B)] KO mice, compared to the corresponding WT littermates. Data are represented as mean ± SEM. *p < 0.05 by Student’s t-test or Mann–Whitney test in accordance with data distribution. Eight animals per genotype were used at each time point (N = 8).