Table 3.

The role of diverse biomolecules.

Different biological factors	Function
TNF-α	Effective pro-inflammatory cytokines
TGF-β	Factors involved in wound healing
IL-6	Key molecules in the early stages of tendon injury and after stress on healthy tendons
MMPs, TIMPs	The ratio is especially essential, and it has a great influence on the formation of tendon collagen
VEGF	Vascular endothelial growth factor plays an important role in blood regulation
NF-κB pathway	Nuclear factor kappa-β, it has a huge impact on the inflammatory response and immune response of cells

TNF-α, tumor necrosis factor-α; TGF-β, transforming growth factor-β; IL-6, interleukin-6; MMPs, matrix metalloprotease; TIMPs, tissue inhibitors of metalloproteinases; VEGF, vascular endothelial growth factor; and NF-kB, nuclear factor kappa-β.