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Itraconazole induced apoptosis in cSCC cells. (A–C) Cell apoptosis at different itraconazole concentrations, as determined using flow cytometry. [mean ± SD (error bars), n = 3; *p ≤ .05; **p ≤ .01; ***p ≤ .001, compared with control group] (D,E) TUNEL measurement of apoptosis in A431 and Colo16 cells visualized with a fluorescent microscope (Scale bar: 100 μm).
