Table 4.
Significant different subclasses of lipids of T0 (n = 26) verse control (n = 10) and T2 (n = 26) verse T0 (n = 26).
| LipidIon | Class | Calmz | IonFormula | RT-(min) | T0 vs. control | T2 vs. T0 | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Fold change | P-value | VIP | Fold Change | P-value | VIP | |||||
| OAHFA(18:1/34:1)-H | OAHFA | 785.7392 | C52 H97 O4 | 20.93825 | 52.16343297 | 0.036918 | 2.29603 | 0.14442499 | 0.003703 | 2.80631 |
| OAHFA(18:1/32:1)-H | OAHFA | 757.7079 | C50 H93 O4 | 19.74312 | 29.63556255 | 0.047356 | 3.88388 | 0.136615378 | 0.004611 | 4.81245 |
| OAHFA(18:1/32:2)-H | OAHFA | 755.6923 | C50 H91 O4 | 18.67636 | 36.6853155 | 0.044402 | 2.04926 | 0.150416143 | 0.005079 | 2.50278 |
| LPC(18:1)+H | LPC | 522.3554 | C26 H53 O7 N1 P1 | 2.829591 | 8.862523744 | 0.039032 | 1.58635 | 0.410042149 | 0.03062 | 1.52317 |
| LPC(18:0)+HCOO | LPC | 568.362 | C27 H55 O9 N1 P1 | 3.790138 | 3.64099302 | 0.039047 | 1.49809 | 0.494036433 | 0.034213 | 1.26986 |
| LPC(18:1)+HCOO | LPC | 566.3463 | C27 H53 O9 N1 P1 | 2.824801 | 7.164012181 | 0.008767 | 2.12477 | 0.381895001 | 0.003515 | 1.85389 |
| LPC(16:0)+HCOO | LPC | 540.3307 | C25 H51 O9 N1 P1 | 2.693533 | 4.427438179 | 0.035098 | 3.57942 | 0.418414154 | 0.017479 | 3.33535 |
| LPC(18:2)+H | LPC | 520.3398 | C26 H51 O7 N1 P1 | 2.251227 | 2.988598263 | 0.000856 | 1.55151 | 0.586953112 | 0.005786 | 1.05027 |
| TG(26:0/16:0/18:1)+Na | TG | 995.8977 | C63 H120 O6 Na1 | 24.44222 | 21.32021673 | 0.020276 | 1.07358 | 0.354541857 | 0.018517 | 1.12173 |
| TG(18:1/18:2/20:5)+H | TG | 903.7436 | C59 H99 O6 | 19.71597 | 5.444758925 | 0.005544 | 1.3387 | 0.489043562 | 0.006754 | 1.65819 |
| TG(16:0/18:2/20:5)+H | TG | 877.728 | C57 H97 O6 | 19.659 | 5.818026726 | 0.004927 | 2.28256 | 0.470568415 | 0.004624 | 1.1926 |
| TG(16:1/18:1/18:2)+NH4 | TG | 872.7702 | C55 H102 O6 N1 | 19.68893 | 6.980513631 | 0.030259 | 1.53642 | 0.387629187 | 0.013507 | 2.03988 |
| Cer(d17:0/2:0)+H | Cer | 330.3003 | C19 H40 O3 N1 | 1.913699 | 3.248423375 | 2.35E-06 | 1.85695 | 0.628695394 | 0.000317 | 1.16972 |
| Cer(d18:1/18:0)+HCOO | Cer | 610.5416 | C37 H72 O5 N1 | 12.32153 | 0.144934423 | 0.001796 | 1.9301 | 15.03077997 | 0.026831 | 3.35324 |
A number of 13 lipids were significantly increased in T0, whereas they were decreased following IPL treatment. The different lipids were OAHFA(18:1/34:1)-H(C52H97O4), OAHFA(18:1/32:1)-H(C50H93O4), OAHFA(18:1/32:2)-H(C50H91O4), LPC(18:1)+H(C26H53O7N1P1), LPC(18:0)+HCOO(C27H55O9N1P1), LPC(18:1)+HCOO (C27H53O9N1P1), LPC(16:0)+HCOO(C25H51O9N1P1), LPC(18:2)+H(C26H51O7N1 P1), TG(26:0/16:0/18:1)+Na(C63H120O6Na1), TG(18:1/18:2/20:5)+H(C59H99O6), TG(16:0/18:2/20:5)+H(C57H97O6), TG(16:1/18:1/18:2)+NH4 (C55H102O6N1), and Cer(d17:0/2:0)+H(C19 H40 O3 N1).
T0, before treatment; T2, after treatment.