Table 2. TSH Levels Within 6 Weeks and 12 Months After Index Date Among Nonswitchers vs Switchers.
Patients, No. (%) | Risk or mean difference (95% CI) | P value | ||
---|---|---|---|---|
Nonswitchers (n = 2780) | Switchers (n = 2780) | |||
TSH level | ||||
Normal (0.3-4.4 mIU/L) | 2298 (82.7) | 2348 (84.5) | Risk difference: −0.018 (−0.038 to 0.002) | .07 |
Abnormal (<0.3 or >4.4 mIU/L) | 482 (17.3) | 432 (15.5) | Risk difference: 0.018 (−0.002 to 0.038) | .07 |
Markedly abnormal (<0.1 or >10 mIU/L) | 87 (3.1) | 69 (2.5) | Risk difference: 0.007 (−0.002 to 0.015) | .14 |
Mean TSH level, (SD), mIU/L | 2.7 (2.3) | 2.7 (3.3) | Mean difference: 0.01 (−0.14 to 0.16) | .94 |
Mean TSH level change from baseline, (SD), mIU/L | 0.51 (2.28) | 0.53 (3.25) | Mean difference: −0.02 (−0.16 to 0.13) | .84 |
Abbreviation: TSH, thyrotropin.