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. 2022 Feb 28;182(4):418–425. doi: 10.1001/jamainternmed.2022.0045

Table 2. TSH Levels Within 6 Weeks and 12 Months After Index Date Among Nonswitchers vs Switchers.

Patients, No. (%) Risk or mean difference (95% CI) P value
Nonswitchers (n = 2780) Switchers (n = 2780)
TSH level
Normal (0.3-4.4 mIU/L) 2298 (82.7) 2348 (84.5) Risk difference: −0.018 (−0.038 to 0.002) .07
Abnormal (<0.3 or >4.4 mIU/L) 482 (17.3) 432 (15.5) Risk difference: 0.018 (−0.002 to 0.038) .07
Markedly abnormal (<0.1 or >10 mIU/L) 87 (3.1) 69 (2.5) Risk difference: 0.007 (−0.002 to 0.015) .14
Mean TSH level, (SD), mIU/L 2.7 (2.3) 2.7 (3.3) Mean difference: 0.01 (−0.14 to 0.16) .94
Mean TSH level change from baseline, (SD), mIU/L 0.51 (2.28) 0.53 (3.25) Mean difference: −0.02 (−0.16 to 0.13) .84

Abbreviation: TSH, thyrotropin.