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. 2022 Feb 28;182(4):418–425. doi: 10.1001/jamainternmed.2022.0045

Table 3. Sensitivity Analysis Using TSH Levels Between 6 and 12 Weeks After Index Date Among Nonswitchers vs Switchers.

Patients No. (%) (n = 675) Risk or mean difference (95% CI) P value
Nonswitchers Switchers
TSH level
Normal (0.3-4.4 mIU/L) 559 (82.8) 565 (83.7) Risk difference: −0.009 (−0.049 to 0.031) .66
Abnormal (<0.3 or >4.4 mIU/L) 116 (17.2) 110 (16.3) Risk difference: 0.009 (−0.031 to 0.049) .66
Markedly abnormal (<0.1 or >10 mIU/L) 28 (4.1) 22 (3.2) Risk difference: 0.009 (−0.011 to 0.029) .39
Mean TSH level, (SD), mIU/L 2.61 (2.73) 2.87 (4.89) Mean difference: −0.26 (−0.68 to 0.16) .23
Mean TSH level change from baseline, (SD), mIU/L 0.44 (2.63) 0.67 (4.85) Mean difference: −0.23 (−0.65 to 0.18) .27

Abbreviation: TSH, thyrotropin.