Table 3. Sensitivity Analysis Using TSH Levels Between 6 and 12 Weeks After Index Date Among Nonswitchers vs Switchers.
Patients No. (%) (n = 675) | Risk or mean difference (95% CI) | P value | ||
---|---|---|---|---|
Nonswitchers | Switchers | |||
TSH level | ||||
Normal (0.3-4.4 mIU/L) | 559 (82.8) | 565 (83.7) | Risk difference: −0.009 (−0.049 to 0.031) | .66 |
Abnormal (<0.3 or >4.4 mIU/L) | 116 (17.2) | 110 (16.3) | Risk difference: 0.009 (−0.031 to 0.049) | .66 |
Markedly abnormal (<0.1 or >10 mIU/L) | 28 (4.1) | 22 (3.2) | Risk difference: 0.009 (−0.011 to 0.029) | .39 |
Mean TSH level, (SD), mIU/L | 2.61 (2.73) | 2.87 (4.89) | Mean difference: −0.26 (−0.68 to 0.16) | .23 |
Mean TSH level change from baseline, (SD), mIU/L | 0.44 (2.63) | 0.67 (4.85) | Mean difference: −0.23 (−0.65 to 0.18) | .27 |
Abbreviation: TSH, thyrotropin.