Table 4.

Univariable and multivariable logistic regression analyses on associated factors for major LARS in colon cancer patients (n=1183).

	n (%)	Univariable			Multivariable
		OR	95%-CI	p-value	OR	95%-CI	p-value
Gender
Male	651 (55.0)	1.00			1.00
Female	532 (45.0)	1.65	1.25 – 2.18	<0.001	1.68	1.26 – 2.23	<0.001
Age
<70 years	647 (54.7)	1.00
≥70 years	536 (45.3)	1.13	0.85 – 1.49	0.41
ASA classification
I-II	1017 (86.0)	1.00
III	149 (12.6)	0.84	0.54 – 1.31	0.45
Missing	17 (1.4)
Time since surgery
2-3 years	384 (32.5)	0.89	0.63 – 1.24	0.48
4-5 years	347 (29.3)	1.15	0.82 – 1.60	0.42
>5 years	452 (38.2)	1.00
Surgical procedure
Right hemicolectomy	527 (44.5)	1.00			1.00
Left/transverse hemicolectomy	133 (11.2)	0.55	0.33 – 0.92	0.02	0.52	0.31 – 0.88	0.02
Sigmoid resection	505 (42.7)	0.77	0.57 – 1.04	0.08	0.75	0.55 – 1.03	0.07
Anterior resection	18 (1.5)	0.89	0.29 – 2.75	0.84	0.78	0.25 – 2.44	0.67
Surgical technique
Laparoscopy	660 (55.8)	1.00
Open	427 (36.1)	1.06	0.79 – 1.43	0.69
Converted to open	94 (7.9)	0.82	0.47 – 1.43	0.49
Missing	2 (0.2)
Temporary diverting ostomy	116 (9.8)	1.54	1.00 – 2.37	0.049	1.71	1.05 – 2.79	0.03
Tumour stage
Stage I-II	810 (68.5)	1.22	0.90 – 1.66	0.20
Stage III-IV	372 (31.4)	1.00
Anastomotic leakage	68 (5.7)	1.59	0.92 – 2.73	0.095	1.27	0.70 – 2.32	0.43
Clavien-Dindo complication grade
Grade 0	788 (66.6)	1.00
Grade I-II	241 (20.4)	1.26	0.89 – 1.77	0.20
Grade III-IV	153 (12.9)	1.34	0.89 – 2.01	0.16
Missing	1 (0.1)
Adjuvant chemotherapy	385 (32.5)	0.81	0.60 – 1.10	0.17