Table 2. Quality of Life and Health Status by Study Group.
| Scale | Median score (range)a | P valueb | ||
|---|---|---|---|---|
| Group A, chemotherapy with placebo | Group B, chemotherapy with bevacizumab | Group C, chemotherapy with bevacizumab (extended) | ||
| FACT-B | 123.0 (67.2-146.0) | 113.5 (54.0-148.0) | 117.0 (42.3-148.0) | .23 |
| FACT-G individual subscale domains | ||||
| Physical | 24.0 (9.0-28.0) | 24.0 (0-28.0) | 24.0 (1.0-28.0) | .97 |
| Social and family | 24.8 (0-28.0) | 24.2 (5.6-28.0) | 24.0 (4.0-28.0) | .47 |
| Emotional | 21.0 (8-24.0) | 20.0 (6.0-24.0) | 21.0 (2.0-24.0) | .03 |
| Functional | 23.0 (6.0-28.0) | 22.0 (4.0-28.0) | 22.0 (4.0-28.0) | .62 |
| Breast cancer–specific | 29.0 (12.0-40.0) | 27.0 (9.0-40.0) | 28.0 (7.0-40.0) | .20 |
| Arm subscale | 17.0 (4.0-20.0) | 16.0 (0-20.0) | 16.0 (0-20.0) | .76 |
| EQ-5D-3L Index | 0.83 (0.28-1.00) | 0.83 (0.20-1.00) | 0.83 (0.17-1.00) | .80 |
| EQ-VAS | 85.0 (20.0-100) | 85.0 (0-100) | 85.0 (0-100) | .79 |
Abbreviations: EQ-5D-3L, EuroQol 5–Dimension 3–Level; EQ-VAS, EuroQol visual analogue scale; FACT-B, Functional Assessment of Cancer Therapy Scale–Breast Cancer; FACT-G, Functional Assessment of Cancer Therapy Scale–General.
a
Higher scores indicate better quality of life. The maximum score for FACT-B is 148; FACT-G physical, social, and functional subscale, 28; FACT-G emotional subscale, 24; breast cancer–specific subscale, 40, arm subscale, 20.
b
Kruskal-Wallis test.