Table 3. Quality of Life and Health Status: BCS vs Mastectomy With and Without Radiation.
| Scale | Median score (range)a | P valueb | ||||
|---|---|---|---|---|---|---|
| BCS | Mastectomy | Mastectomy without PMRT vs BCS | Mastectomy with PMRT vs BCS | Mastectomy with vs without PMRT | ||
| Without PMRT | With PMRT | |||||
| FACT-B | 120.0 (56.2-148.0) | 117.3 (53.3-146.0) | 113.5 (42.3-148.0) | .26 | .003 | .23 |
| FACT-G individual domains | ||||||
| Physical | 25.0 (0-28.0) | 25.0 (2.8-28.0) | 24.0 (1.0-28.0) | .65 | .02 | .11 |
| Social and family | 25.0 (0-28.0) | 24.0 (4.7-28.0) | 24.0 (8.0-28.0) | .49 | .23 | .66 |
| Emotional | 20.0 (9.0-24.0) | 20.0 (7.0-24.0) | 20.0 (2.0-24.0) | .44 | .03 | .32 |
| Functional | 23.0 (4.0-28.0) | 22.0 (5.0-28.0) | 21.0 (4.0-28.0) | .23 | .06 | .79 |
| Breast cancer–specific | 30.0 (9.0-40.0) | 29.0 (7.0-40.0) | 27.0 (7.0-40.0) | .06 | <.001 | .17 |
| Arm subscale | 17.0 (0-20.0) | 17.0 (1-20.0) | 15.0 (0-20.0) | .63 | <.001 | <.001 |
| EQ-5D-3L Index | 0.83 (0.24-1.00) | 0.83 (0.20-1.00) | 0.83 (0.17-1.00) | .16 | .05 | .89 |
| EQ-VAS | 86.5 (30.0-100) | 85.0 (20.0-100) | 80.0 (0-100) | .33 | .003 | .11 |
Abbreviations: BCS, breast conserving surgery; EQ-5D-3L, EuroQol 5–Dimension–3 Level; EQ-VAS, EuroQol visual analogue scale; FACT-B, Functional Assessment of Cancer Therapy Scale–Breast Cancer; FACT-G, Functional Assessment of Cancer Therapy Scale–General; PMRT, postmastectomy radiation.
a
Higher scores indicate better quality of life.
b
P values based on Wilcoxon rank sum test.