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. 2022 Feb 28;5(2):e220254. doi: 10.1001/jamanetworkopen.2022.0254

Table 4. Factors Associated With Total FACT-B Scores at 18 Months.

Factor Univariate model Multivariable modela
Coefficient (95% CI) P value Coefficient (95% CI) P value
Mastectomy
Without PMRT vs BCS −3.1 (−8.7 to 2.5) .28 −2.9 (−8.6 to 2.6) .29
With PMRT vs BCS −6.6 (−11.1 to −2.1) .004 −5.5 (−10.1 to −0.9) .02
Age (years) 0.1 (−0.1 to 0.3) .15 0.1 (−0.06 to 0.3) .17
Asian, Black, or American Indian or Alaska Native vs White −7.3 (−13.2 to −1.3) .02 −7.3 (−13.2 to −1.4) .02
No college education vs college educationb −0.71 (−4.9 to 3.4) .74 NA NA
ER/PR positive vs negative −5.1 (−9.4 to −0.9) .02 −4.4 (−8.8 to 0.07) .05
Tumor size >2 cm vs ≤2 cm −3.7 (−7.9 to 0.5) .09 NA NA
Nodal status positive vs negative −3.3 (−7.9 to 1.3) .15 NA NA

Abbreviations: BCS, breast conserving surgery; ER, estrogen receptor; FACT-B, Functional Assessment of Cancer Therapy Scale–Breast Cancer; NA, not applicable; PR, progesterone receptor; PMRT, postmastectomy radiation.

a

Based on linear regression model with lowest Akaike information criterion.

b

Education status was missing or unknown for 30 patients and was not assessed in the multivariable model.