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. 2021 Dec 1;48(2):474–484. doi: 10.1093/schbul/sbab137

Fig. 1.

Fig. 1.

Effects of SOMCL-668 on acute and chronic phencyclidine-induced schizophrenia-related behaviors. (A) Experimental outline of acute studies. (B) PPI (%) was assessed using a startle stimulus intensity of 120 dB and prepulse intensities of 76, 83 and 87 dB. (C) Representative specimen traces of locomotor activity and summary bar graph of distance traveled. (D) Experimental outline of chronic studies. Social interaction (E) is presented as interaction time (s) and novel object recognition is presented as exploration time (s) for the familiar and novel objects (F) and as discrimination index (G). Data are shown as mean ± SEM; n = 10–12 mice per group. Statistical analysis was by one-way ANOVA (C, E and G) and two-way ANOVA (B and F); * P < .05, ** P < .01, *** P < .001.