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Model workflow. The Kalman filter combines measurements from the real system with predictions from the dynamical model, which extends a SEIR model. Empirical data are daily positive cases, shown in blue as the smoothed moving average, and wastewater sampled data, shown in orange with unit of measure of RNA copies/day/100,000 equivalent inhabitants (example for Luxembourg). Details of the SEIR blocks are described in Section 2.4.
