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. 2022 Feb 22;7(9):8150–8157. doi: 10.1021/acsomega.2c00113

Table 1. Binding Affinity Measured by Fluorescence Quenching and ELISA Assays.

system GQD-based fluorescence quenching ELISA-like assay
LL-37 & HNP1-attached GQDs 8 ± 1 nM 9 ± 1 nM
LL-37-attached GQDs 12 ± 1 nM 13 ± 1 nM
HNP1-attached GQDs 120 ± 20 nM 116 ± 20 nM
LL-37 peptide   16 ± 1 nM
HNP1 peptide   160 ± 40 nM
ACE2   8 ± 1 nM
GQDs 3.8 ± 0.6 μM 3.2 ± 0.5 μM