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. 2022 Feb 16;2022:1599747. doi: 10.1155/2022/1599747

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Copyright © 2022 Caizhen Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Choline diet remarkably increased the serum levels of TMAO in mice. (a) Representative results for the concentrations of TMAO in the serum of mice in each group detected by UPLC-MS/MS at 24 h and 72 h after sham operation or ICH. (b) Dot plots show the quantitative analysis of the concentrations of TMAO in the serum of mice that received a regular diet/choline diet at 24 h and 72 h after sham operation or ICH. ^∗p < 0.05 compared with the sham+control group (n = 6 mice/group); ^#p < 0.05 compared with the ICH+control group (n = 6 mice/group).