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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Eur Cell Mater. 2021 Sep 22;42:156–165. doi: 10.22203/eCM.v042a12

Fig. 4. Elevated anti-Isd IgG4 antibody levels in bone infection patients.

Fig. 4.

The sera described in Fig. 1 were analysed for IgG antibodies specific for IsdA, IsdB, and IsdH using a Luminex to determine: (a) total IgG MFI, (b) MFI for IgG4 specific antibodies, and (c) IgG4 MFI divided by total IgG MFI (RATIO). The data are presented for each patient with the median for the group. IgG4 to IgG RATIO represents the MFI for IgG4 divided by the MFI for total IgG normalised by Ctrl ratios such that the Ctrl median ratio is a value of 1. **p < 0.01, Wilcoxon rank-sum tests with adaptive Hochberg multiplicity adjustment.